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Record type:	stať ve sborníku (D)
Home Department:	Ústav laboratorní medicíny (11430)
Title:	Distribution of somatic mutations in PIK3CA gene in breast colorectal and colorectal Czech cancer patients - selected colorectal cancer patients with angiogenesis inhibitors treatment
Citace	Šimková, J., Urbanovská, I., Měch, R., Žmolíková, J., Kubová, B., Vaňková, K., Trombik, L., Dvořáčková, N., Dvořáčková, J., Drábek, J. a Uvírová, M. Distribution of somatic mutations in PIK3CA gene in breast colorectal and colorectal Czech cancer patients - selected colorectal cancer patients with angiogenesis inhibitors treatment. In: Conference on Molecular Analysis for Personalised Therapy (MAP): ANN ONCOL 2019-11-07 London, ENGLAND. ISSN 0923-7534.

Subtitle
Publication year:	2019
Obor:	Onkologie a hematologie
Number of pages:	1
Page from:	neuvedeno
Page to:	neuvedeno
Form of publication:	Elektronická verze
ISBN code:	neuvedeno
ISSN code:	0923-7534
Proceedings title:	ANN ONCOL
Proceedings:	Mezinárodní
Publisher name:	neuvedeno
Place of publishing:	neuvedeno
Country of Publication:	Sborník vydaný v zahraničí
Název konference:	Conference on Molecular Analysis for Personalised Therapy (MAP)
Místo konání konference:	London, ENGLAND
Datum zahájení konference:
Typ akce podle státní příslušnosti účastníků:	Evropská akce
WoS code:	000496763900087
EID:

Key words in English:	mutations, oncology
Annotation in original language:	Mutation profiling of tumours for treatment options is reality in many types of cancer and biomarkers eg. KRAS, EGFR are well established in personalised medicine. Phosphatidyl 3-kinases (PI3K) are a family of lipid kinases involved in many cellular processes, including cell growth, proliferation, differentiation, motility, and survival. Mutation of PIK3CA gene has been implicated in the pathogenesis of several cancers, but their prognostic/predictive/therapeutic implications are still controversial.
Annotation in english language:

References

Reference

R01:	RIV/61988987:17110/19:A2002348

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