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Publikační činnost


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Typ záznamu * : stať ve sborníku (D)
Domácí pracoviště * : Ústav fyziologie a patofyziologie (11501)
Název * : Chronobiological aspects of general anesthesia in rat myocardial electrophysiology
Citace : Švorc, P. Chronobiological aspects of general anesthesia in rat myocardial electrophysiology. In: ACTA PHYSIOLOGICA 2017 New York. HOBOKEN 07030-5774, NJ USA: WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2017. s. 114-114. ISSN 1748-1708.
Podnázev :
Rok * : 2017
Obor * : Fyziologie
Počet stran * : 1
Strana od * : 114
Strana do * : 114
Forma vydání * : Tištená verze
Kód ISBN * : neuvedeno
Kód ISSN : 1748-1708
Název sborníku * : ACTA PHYSIOLOGICA
Sborník : Mezinárodní
Název nakladatele * : WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
Místo vydání * : HOBOKEN 07030-5774, NJ USA
Stát vydání : Sborník vydaný v zahraničí
Název konference :
Místo konání konference * : New York
Datum zahájení konference * :
Typ akce podle státní
příslušnosti účastníků akce * :
Evropská akce
Kód UT WoS : 000408842000206
EID :
Klíčová slova anglicky * :
myocardial electrophysiological parameters
Popis v původním jazyce * :
The specific aim of the present study, with respect to dependence on the light–dark (LD) cycle under in vivo conditions in spontaneously breathing rats was to review initial state in electrophysiological parameters that may predict the development of heart rhythm disorders in pentobarbital (40 mg/kg), ketamine–xylazine (100 + 15 mg/kg) and zoletil (30 mg/kg) anaesthetized animals. The study was performed using female Wistar rats that were adaptated to an LD cycle (12 h:12 h). Heart rate, PQ and QT intervals were evaluated for their dependence on the LD cycle. The longest PQ interval duration is under zoletil anaesthesia in the light period and the longest QT interval duration is under ketamine–xylazine anaesthesia in both light periods. We concluded that the most significant predisposition toward the development of ventricular arrhythmias originating from disorders of impulse production and conduction occurred under zoletil anaesthesia in the light period; those resulting from disorders in the dispersion of refractory periods occurred under ketamine–xylazine anaesthesia in both the light periods.
Popis v anglickém jazyce * :
The specific aim of the present study, with respect to dependence on the light–dark (LD) cycle under in vivo conditions in spontaneously breathing rats was to review initial state in electrophysiological parameters that may predict the development of heart rhythm disorders in pentobarbital (40 mg/kg), ketamine–xylazine (100 + 15 mg/kg) and zoletil (30 mg/kg) anaesthetized animals. The study was performed using female Wistar rats that were adaptated to an LD cycle (12 h:12 h). Heart rate, PQ and QT intervals were evaluated for their dependence on the LD cycle. The longest PQ interval duration is under zoletil anaesthesia in the light period and the longest QT interval duration is under ketamine–xylazine anaesthesia in both light periods. We concluded that the most significant predisposition toward the development of ventricular arrhythmias originating from disorders of impulse production and conduction occurred under zoletil anaesthesia in the light period; those resulting from disorders in the dispersion of refractory periods occurred under ketamine–xylazine anaesthesia in both the light periods.
Typ zdroje financování výsledku * : Jiné veřejné zdroje
Seznam projektů :
ID Projektu Název projektu
Seznam ohlasů : 
Ohlas
R01: RIV/61988987:17110/17:A20020S8

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