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Typ záznamu * : stať ve sborníku (D)
Domácí pracoviště * : Lékařská fakulta (11000)
Název * : Intraplaque hemorrhage in symptomatic and asymptomatic progressive carotid artery stenosis-a pilot study
Citace : Školoudík, D. Intraplaque hemorrhage in symptomatic and asymptomatic progressive carotid artery stenosis-a pilot study. In: 4th Congress of the European-Academy-of-Neurology (EAN): EUROPEAN JOURNAL OF NEUROLOGY 2018 Lisabon Portugalsko. HOBOKEN 07030-5774, NJ USA: WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2018. s. 156-156. ISSN 1351-5101.
Podnázev :
Rok * : 2018
Obor * : Neurologie, neurochirurgie, neurovědy
Počet stran * : 1
Strana od * : 156
Strana do * : 156
Forma vydání * : Elektronická verze
Kód ISBN * : neuvedeno
Kód ISSN : 1351-5101
Název sborníku * : EUROPEAN JOURNAL OF NEUROLOGY
Sborník : Mezinárodní
Název nakladatele * : WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
Místo vydání * : HOBOKEN 07030-5774, NJ USA
Stát vydání : Sborník vydaný v zahraničí
Název konference : 4th Congress of the European-Academy-of-Neurology (EAN)
Místo konání konference * : Lisabon Portugalsko
Datum zahájení konference * :
Typ akce podle státní
příslušnosti účastníků akce * :
Evropská akce
Kód UT WoS : 000435272001113
EID :
Klíčová slova anglicky * :
Intraplaque haemorhage
Popis v původním jazyce * :
Background and aims Intraplaque hemorrhage (IPH) belongs to potential mechanisms of unstable plaque development. Study aims to compare the IPH occurrence in patients with asymptomatic stable (ASS), asymptomatic progressive (APS) and symptomatic (SS) carotid artery stenosis ˃50%. Methods Serial duplex ultrasound (DUS) in a 6-month period and magnetic resonance imaging (MRI) using axial 3DT1w sequence were used for IPH detection in patients with carotid stenosis. Stenoses in patients with ipsilateral stroke/transient ischemic attack within previous 4 weeks or acute ischemic lesion on diffusion-weighted MRI were evaluated as symptomatic. Stenoses with progression of ˃10% since last DUS examination were evaluated as progressive. Echolucent part of atherosclerotic plaque ˃8 mm2 on DUS and hyperintensity on 3DT1w-MRI were evaluated as IPH. Differences in IPH occurrence between ASS, APS and SS patients were statistically evaluated. Results Totally 32 patients (18 males, mean age 71.3±7.7 years) were enrolled during 18 months; 5 patients with ASS, 18 with APS and 9 with SS. MRI examination was not performed in 3 ASS and 1 SS patient. IPH was detected using DUS/MRI in 1 (20%)/2 (40%) of ASS patients, 9 (50%)/8 (53%) of APS patients, and 5 (56%)/4 (50%) of SS patients (p˃0.05 in all cases). IPH on both DUS and MRI were detected in none of ASS patients, 5 (28%) APS patients and 3 (33%) SS patients (p˃0.05 in all cases). Conclusion No significant difference in IPH occurrence was found between ASS, APS and SS patients. Totally 200 patients will be enrolled to the ongoing study.
Popis v anglickém jazyce * :
Background and aims Intraplaque hemorrhage (IPH) belongs to potential mechanisms of unstable plaque development. Study aims to compare the IPH occurrence in patients with asymptomatic stable (ASS), asymptomatic progressive (APS) and symptomatic (SS) carotid artery stenosis ˃50%. Methods Serial duplex ultrasound (DUS) in a 6-month period and magnetic resonance imaging (MRI) using axial 3DT1w sequence were used for IPH detection in patients with carotid stenosis. Stenoses in patients with ipsilateral stroke/transient ischemic attack within previous 4 weeks or acute ischemic lesion on diffusion-weighted MRI were evaluated as symptomatic. Stenoses with progression of ˃10% since last DUS examination were evaluated as progressive. Echolucent part of atherosclerotic plaque ˃8 mm2 on DUS and hyperintensity on 3DT1w-MRI were evaluated as IPH. Differences in IPH occurrence between ASS, APS and SS patients were statistically evaluated. Results Totally 32 patients (18 males, mean age 71.3±7.7 years) were enrolled during 18 months; 5 patients with ASS, 18 with APS and 9 with SS. MRI examination was not performed in 3 ASS and 1 SS patient. IPH was detected using DUS/MRI in 1 (20%)/2 (40%) of ASS patients, 9 (50%)/8 (53%) of APS patients, and 5 (56%)/4 (50%) of SS patients (p˃0.05 in all cases). IPH on both DUS and MRI were detected in none of ASS patients, 5 (28%) APS patients and 3 (33%) SS patients (p˃0.05 in all cases). Conclusion No significant difference in IPH occurrence was found between ASS, APS and SS patients. Totally 200 patients will be enrolled to the ongoing study.
Typ zdroje financování výsledku * : Jiné veřejné zdroje
Seznam projektů :
ID Projektu Název projektu
Seznam ohlasů : 
Ohlas
R01: RIV/61988987:17110/18:A20020PX

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