Publ3 search

Error:

Javascript is disabled in this browser. This page requires Javascript. Modify your browser's settings to allow Javascript to execute. See your browser's documentation for specific instructions.

Publikační činnost

Probíhá načítání, čekejte prosím...

Typ záznamu * :	článek v odborném periodiku (J)
Domácí pracoviště * :	Environmentální centrum ENC (31990)
Název * :	Liver regeneration during the associating liver partition and portal vein ligation for staged hepatectomy procedure in Sus scrofa is positively modulated by stem cells
Citace :	Bartas, M., Červeň, J., Oppelt, J., Peteja, M., Vávra, P., Zonča, P., Procházka, V., Brázda, V. a Pečinka, P. Liver regeneration during the associating liver partition and portal vein ligation for staged hepatectomy procedure in Sus scrofa is positively modulated by stem cells. Oncology letters. 2018, č. 15, s. 6309-6321. ISSN 1792-1074.

Podnázev :
Rok * :	2018
Obor * :
Kód ISSN * :	1792-1074
Oficiální název periodika * :	Oncology letters
Stát vydavatele periodika * :	Řecká republika
Svazek periodika * :	15
Číslo periodika v rámci svazku * :	May
Číslo článku :
Ročník :
Počet stran článku * :	12
Strana od * :	6309
Strana do * :	6321
Kód UT WoS :	000431825900030
EID :
Poddruh recenzovaného článku :	Článek v impaktovaném časopise (Jimp)

Klíčová slova anglicky * :	liver regeneration; Sus scrofa; associating liver partition and portal vein ligation for staged hepatectomy; stem cells; transcriptome sequencing
Popis v původním jazyce * :	This present study investigated the impact of the application of stem cells to liver regeneration following the first stage of associating liver partition and portal vein ligation for staged hepatectomy (ALPPS). The experiment was conducted on a pig model (n=6, 3 that did not receive application of stem cells, 3 that received application stem cells). Collected samples of liver (day 0 and 9 following surgery) were subjected to complete transcriptome sequencing. In total, 39 differen- tially expressed genes were found in the group without the application of the stem cells (genes of unwanted processes such as fibrosis and inflammation). In the group that did receive application of stem cells, no significantly differentially expressed genes were found, indicating a properly regenerated liver remnant. The present study therefore demonstrated, to the best of our knowledge for the first time, the positive effect of stem cells application in the liver regeneration process during ALPPS procedure in the pig model
Popis v anglickém jazyce * :

Typ zdroje financování výsledku * :

Projekty CEP/Záměry CEZ

Seznam projektů :

ID Projektu	Název projektu

Seznam ohlasů :

Ohlas

R01:	RIV/61988987:17310/18:A1901UJU

Complementary Content

${loading}