Alzheimer´s disease, Epidemiology, risk factors

n 2010 research project Epidemiology and Genetics of Alzheimer´s disease has been launched in the Czech Republic to asses the effect of those risk factors on the group of 800 cases of AD and group of 800 controls. Pilot evaluation presents results from 361 cases and 130 controls. It is suggested, that patients with AD have more often cardiovascular disease in their history, they drink more alcohol and more smoke. In this pilot evaluation there has not been found statistically significant difference in diabetes mellitus, hypertension and cerebrovascular disease, probably because of small sample size. Relationship among the ApoE4 allele and the higher risk of AD has been found. Supported by the Czech Ministry of Health grant project no. NT11152-6/2010.

n 2010 research project Epidemiology and Genetics of Alzheimer´s disease has been launched in the Czech Republic to asses the effect of those risk factors on the group of 800 cases of AD and group of 800 controls. Pilot evaluation presents results from 361 cases and 130 controls. It is suggested, that patients with AD have more often cardiovascular disease in their history, they drink more alcohol and more smoke. In this pilot evaluation there has not been found statistically significant difference in diabetes mellitus, hypertension and cerebrovascular disease, probably because of small sample size. Relationship among the ApoE4 allele and the higher risk of AD has been found. Supported by the Czech Ministry of Health grant project no. NT11152-6/2010.