Alzheimer's disease, risk factors, epidemiology, genes, apolipoprotein E

Alzheimer's disease (AD) is the most common form of dementia. AD represents an important public health problem. Its aetiology is still unknown and that is why it is necessary to study all potential risk factors which may contribute to the development of this disease. Three basic etiological hypotheses of the development of AD have been formulated: genetic, vascular and psychosocial. Important details about pathologies responsible for AD including Amyloid cascade hypothesis, Tau protein and apolipoprotein E biology are today very well described.

Alzheimer's disease (AD) is the most common form of dementia. AD represents an important public health problem. Its aetiology is still unknown and that is why it is necessary to study all potential risk factors which may contribute to the development of this disease. Three basic etiological hypotheses of the development of AD have been formulated: genetic, vascular and psychosocial. Important details about pathologies responsible for AD including Amyloid cascade hypothesis, Tau protein and apolipoprotein E biology are today very well described.