Bone mineral density, Obesity, Laparoscopic sleeve gastrectomy, Women

The aim of the study was to establish longitudinal bone changes in obese women after laparoscopic sleeve gastrectomy (LSG). 29 women at baseline mean age of 40.41 +/- 9.26 years and with mean body mass index (BMI) of 43.07 +/- 4.99 kg/m(2) were included in a 6-month study. Skeletal status at hip and spine was assessed at baseline, as well as in 6 months after surgery. Baseline body weight was 117.5 +/- 18.4 kg. At 6 months, BMD decreased significantly for spine by 1.24 %, FN 6.99 %, and TH 5.18 %. After 6 months, the corresponding, significant decreases in individual subjects were found in 72 %, 86 %, and 38 % of woman, respectively. Those with a significant loss of FN BMD tended to lose more weight (30 +/- 9.47 versus 23.25 +/- 6.08 kg, p = 0.061) than others; women with a significant decrease of FN BMD lost more weight than those with no such decrease (30.43 +/- 8.07 versus 15 +/- 1.91 kg). LSG proved efficient for body weight reduction, however, with a parallel decline in bone mineral density.