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Publikační činnost

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Typ záznamu:	článek v odborném periodiku (J)
Domácí pracoviště:	Ústav klinické farmakologie (11560)
Název:	Cyclosporine A area-under-time-concentration-curve in rheumatologic patients after the first dose. Which of the sparse sampling strategies will predict the best?
Citace	Kořístková, B., Grundmann, M., Suchý, D., Peřinová, I., Brozmanová, H. a Mayer, O. Cyclosporine A area-under-time-concentration-curve in rheumatologic patients after the first dose. Which of the sparse sampling strategies will predict the best?. INT J CLIN PHARM TH. 2011, roč. 49, č. 49, s. 311-320. ISSN 0946-1965.

Podnázev
Rok vydání:	2011
Obor:	Farmakologie a lékárnická chemie
Kód ISSN:	0946-1965
Oficiální název periodika:	INT J CLIN PHARM TH
Stát vydavatele periodika:	Spolková republika Německo
Svazek periodika:	49
Číslo periodika v rámci svazku:	5
Číslo článku:
Ročník:	49
Počet stran článku:	10
Strana od:	311
Strana do:	320
Kód UT WoS:
EID:
Poddruh recenzovaného článku:	Článek v impaktovaném časopise (Jimp)

Klíčová slova anglicky:	cyclosporine A; sparse sampling strategy; AUC; rheumatologic diseases
Popis v původním jazyce:	The aim of the present study was to validate the limited sampling strategies (LSS:s) for prediction of AUC of cyclosporine A (CsA) after the first dose in rheumatologic patients. Blood samples were collected at 0, 0.5, 1, 1.5, 2, 3, 4, 6, 8, and 12 hours after taking the first dose. Altogether 115 LSS:s obtained from the literature were validated. A linear trapezoidal rule was used as a reference method. Mean percentage prediction error (%PE) < +/- 15% and maximal one value of absolute %PE > 30% were considered to be acceptable. The root mean squared error (RMSE) was evaluated for equations that passed the criteria.
Popis v anglickém jazyce:	The aim of the present study was to validate the limited sampling strategies (LSS:s) for prediction of AUC of cyclosporine A (CsA) after the first dose in rheumatologic patients. Blood samples were collected at 0, 0.5, 1, 1.5, 2, 3, 4, 6, 8, and 12 hours after taking the first dose. Altogether 115 LSS:s obtained from the literature were validated. A linear trapezoidal rule was used as a reference method. Mean percentage prediction error (%PE) < +/- 15% and maximal one value of absolute %PE > 30% were considered to be acceptable. The root mean squared error (RMSE) was evaluated for equations that passed the criteria.

Seznam ohlasů

Ohlas

R01:	RIV/61988987:17110/11:A12012YB

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