Hodgkin lymphoma bone involvement prognostic factors radiotherapy

We retrospectively analyzed 103 patients with Hodgkin?s disease treated at our institution between 1995 and 2000. We recorded the incidence of bone involvement, involved localities and basic characteristics of the subgroup of patients. We recorded a total of 18 cases of bone involvement (17,5 per cent of all cases) - 15 primary lesions and three skeletal relapses. Concurrent nodal involvement was present in all cases. Most frequently involved were lumbar vertebrae. At present time, 16 patients are alive without any evidence of disease, one patient is being treated with salvage therapy and one patient expired due to disease progression. Median overall survival is 14 months. Bone involvement is not an adverse predictive factor for treatment response.