Ames test, antimutagenicity, DNA strand scission assay, Vitis vinifera

Using DNA strand scission assay and the Ames test with Salmonella typhimurium His?, an ability of the extract from Vitis vinifera grapes to efficiently inhibit oxidative damage of DNA was documented. No potential genotoxicity of the extract was detected. The results extend the knowledge of beneficial biological effects of compounds isolated from natural raw materials and bring further evidence of the extract to be an interesting source of compounds with protective biological effect and applicability at food industry.