4HAIE study; magnetic resonance imaging; knee; biomechanics

The purpose of this study was to investigate the association between maximal internal knee adduction moment (KAM) during running and the lateral knee cartilage structure in healthy adults. 1104 participants 18-65 years old participated in this study. Biomechanics of the lower extremity during running at the individual’s self-preferred speed were recorded using motion capture system and force plates. A 1.5T MRI scan was used to determine T2 relaxation time of the lateral central femoral cartilage. When controlled for age, sex, running distance and morphological findings of a radiologist in a statistical model, the KAM (OR = 0.95, CI 0.80-1.12) did not significantly influence T2. The KAM did not appear to increase the odd of having a higher T2 relaxation time of the lateral central femoral cartilage indicating that this load may not be related to the deterioration of the collagen structure.

The purpose of this study was to investigate the association between maximal internal knee adduction moment (KAM) during running and the lateral knee cartilage structure in healthy adults. 1104 participants 18-65 years old participated in this study. Biomechanics of the lower extremity during running at the individual’s self-preferred speed were recorded using motion capture system and force plates. A 1.5T MRI scan was used to determine T2 relaxation time of the lateral central femoral cartilage. When controlled for age, sex, running distance and morphological findings of a radiologist in a statistical model, the KAM (OR = 0.95, CI 0.80-1.12) did not significantly influence T2. The KAM did not appear to increase the odd of having a higher T2 relaxation time of the lateral central femoral cartilage indicating that this load may not be related to the deterioration of the collagen structure.